Imaging genetics

Imaging and genetics of neurodevelopmental disorders

Genetic diagnoses for epilepsy and other neurodevelopmental disorders are becoming increasingly prevalent, but symptoms, prognoses and optimal treatment strategies vary even among those with the same genetic mutation. This project aims to develop machine learning methods to link genetic diagnosis, brain development and neurodevelopmental profiles in rare genetic cohorts.

Cortical gene expression in SCN1A. Wagstyl et al., eLife 2023